Respiratory muscle involvement in multiple sclerosis

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Respiratory muscle involvement in multiple sclerosis.

Respiratory complications are common in the terminal stages of multiple sclerosis and contribute to mortality in these patients. When respiratory motor pathways are involved, respiratory muscle weakness frequently occurs. Although it is well established that weakness of the respiratory muscles produces a restrictive ventilatory defect, the degree of muscle weakness and pulmonary function are po...

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Respiratory muscle function and exercise capacity in multiple sclerosis.

Patients with multiple sclerosis (MS) show a poor exercise tolerance. A reduction in respiratory muscle strength has also been reported. The purpose of this study was to evaluate whether reduction in exercise tolerance was related to respiratory muscle dysfunction. Twenty four multiple sclerosis patients (mean +/- SD age: 48 +/- 9 yrs, duration of illness 12.2 +/- 6 yrs, severity of illness as ...

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Skeletal muscle involvement in systemic sclerosis.

The nature and extent of muscle involvement in systemic sclerosis has been the subject of considerable controversy from which it is difficult to form a coherent concept. Clinical evaluation yields an estimate of significant abnormality, varying from none (Norton, Hurd, and Ziff, 1966) to over 60 per cent. (Medsger and Rodnan, 1966). Serum enzyme studies appear to be of little value, since the a...

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Respiratory muscle function in amyotrophic lateral sclerosis.

Few data exist concerning expiratory muscle function in amyotrophic lateral sclerosis (ALS). We studied 26 patients with ALS (16 with respiratory symptoms and 10 without) and measured the maximal static expiratory mouth pressure (MEP), the gastric pressure during a maximal cough (Cough Pga), and the gastric pressure after magnetic stimulation of the lower thoracic nerve roots (Tw Pga). These me...

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Evaluation of Thoracic Kyphosis Angle and Respiratory Functions in Patients with Multiple Sclerosis

Background. Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease. Muscle weakness, tremors, balance disorders, and gait instability are observed in MS patients. Also, respiratory muscles weakness can lead to decreased respiratory capacity, resulting in pneumonia and acute respiratory failure. Objectives. This study evaluates thoracic kyphosis angle (TKA) and respiratory functi...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1999

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.99.13244999